Flashcard · Salivary Gland Disorders
What are the degenerative salivary gland disorders (Sjogren's syndrome and sialosis)?
Answer
Clinical relevance. Recognising Sjogren's and sialosis distinguishes degenerative gland disorders from infection and tumour.
More Detail
Degenerative salivary gland disorders
Sjogren's syndrome and sialosis cause gland dysfunction or enlargement without infection or tumour.
Sjogren's syndrome
- An autoimmune disorder with lymphocytic infiltration of the salivary and lacrimal glands.
- Causes dry mouth (xerostomia) and dry eyes (keratoconjunctivitis sicca); may be primary or secondary (e.g. with rheumatoid arthritis).
- Associated with an increased risk of lymphoma.
Sialosis
- A non-inflammatory, non-neoplastic bilateral painless enlargement of the salivary glands (especially the parotids).
- Associated with diabetes mellitus, alcoholism, malnutrition/eating disorders, and certain drugs.
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