Regarding androgen insensitivity syndrome, which of the following statements are TRUE?

• A. False: Breast development is normal in AIS, not absent.
• B. True
• C. False: Height is normal, not short, in AIS.
• D. True
• E. False: Pubic and axillary hair are scanty or absent, not abundant.

Androgen insensitivity syndrome (AIS) features

• 46,XY with absent/inactive androgen receptors -> develops along female lines.
• Normal breast development (testosterone aromatised to oestrogen).
• Primary amenorrhoea with a short blind-ending vagina, no cervix, absent uterus (testes secrete MIS, so Mullerian structures regress).
• Scanty/absent pubic and axillary hair (androgen-dependent).
• Normal height; intra-abdominal/inguinal testes (gonadectomy for cancer risk).

Why A is false

Breast development is normal, not absent.

Why B is true

Primary amenorrhoea with a short blind vagina occurs.

Why C is false

Height is normal, not short.

Why D is true

Mullerian structures (uterus) are absent.

Why E is false

Pubic and axillary hair are scanty/absent, not abundant.