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Single Best Answer (SBA) · Maternal Infections in Pregnancy

A neonate born to a mother with untreated syphilis later develops notched teeth, interstitial keratitis and sensorineural deafness. Which single triad does this represent?

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Answer: A. Hutchinson's triad of late congenital syphilis

Congenital syphilis

Untreated maternal syphilis can cause congenital infection.

Hutchinson's triad (late congenital syphilis)
  • Hutchinson's teeth (notched incisors).
  • Interstitial keratitis.
  • Sensorineural (eighth nerve) deafness.
Other features
  • Early: hepatosplenomegaly, fever, rash, failure to thrive.
  • Late: saddle nose, sabre tibia, osteochondritis.
Prevention
  • Antenatal screening (VDRL) and treatment with penicillin prevent congenital syphilis.

So this is Hutchinson's triad of late congenital syphilis.

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