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True/False MCQ · Maternal Physiology in Pregnancy

Regarding renal changes in normal pregnancy, which of the following statements are TRUE?

Decide whether each statement is true or false.

  1. AGFR falls in pregnancy
  2. BSerum creatinine and urea fall
  3. CGlycosuria can occur with normal blood glucose
  4. DRenal blood flow increases
  5. EGFR rises by up to about 50% by the second trimester
Show answers and explanation
  • A. False: GFR rises, not falls, in pregnancy.
  • B. True
  • C. True
  • D. True
  • E. True

Renal changes

  • GFR rises up to 50% by T2; renal blood flow up to 80%.
  • Lower creatinine, urea, uric acid; glycosuria with normal blood glucose.
Why A is false

GFR rises, not falls.

Why B is true

Creatinine and urea fall.

Why C is true

Glycosuria can occur with normal blood glucose.

Why D is true

Renal blood flow increases.

Why E is true

GFR rises up to ~50% by T2.

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