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True/False MCQ · Neonatal Respiratory Distress

Concerning blood gases and oxygen therapy in the newborn, the following statements are correct:

Decide whether each statement is true or false.

  1. AA normal newborn pH is approximately 7.35-7.45
  2. BAn arterial PaCO2 of 60 mmHg is normal in a newborn
  3. CThe target oxygen saturation for a preterm baby is around 90%
  4. DHigh oxygen levels are beneficial and should be maximised in preterm babies
  5. EA capillary sample gives an accurate measure of oxygenation (pO2)
Show answers and explanation
  • A. True
  • B. False: A PaCO2 of 60 mmHg is raised (normal 35-45 mmHg), not normal.
  • C. True
  • D. False: High oxygen is harmful in preterm babies and should be titrated, not maximised.
  • E. False: An accurate pO2 cannot be taken from a capillary (or venous) sample; an arterial sample/SpO2 is needed.

Blood gases and oxygen therapy

  • A normal newborn pH is ~7.35-7.45 (PaCO2 35-45 mmHg, PaO2 50-80 mmHg).
  • A PaCO2 of 60 mmHg is raised (normal 35-45), indicating a ventilatory problem.
  • The target saturation for a preterm baby is ~90% (term ~95%).
  • High oxygen is harmful in preterm babies (brain/eyes), so it is titrated, not maximised.
  • An accurate pO2 (oxygenation) cannot be taken from a capillary (or venous) sample - an arterial sample/SpO2 is needed.
Why A is true

Normal newborn pH is ~7.35-7.45.

Why B is false

A PaCO2 of 60 mmHg is raised, not normal.

Why C is true

Preterm target saturation is ~90%.

Why D is false

High oxygen is harmful in preterm babies.

Why E is false

Capillary samples do not give an accurate pO2.

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