Single Best Answer (SBA) · Colorectal Cancer
A 65-year-old woman presents with left-sided lower abdominal pain, iron-deficiency anaemia and a palpable mass in the left iliac fossa. What is the most likely cause?

Show answer and explanation
Answer: B. Carcinoma of the sigmoid (left) colon
Left-sided colorectal carcinoma
Left-sided (descending/sigmoid) colon cancer commonly presents with left-sided abdominal pain, anaemia and a palpable mass, and with altered bowel habit and obstruction because the left colon has a narrower lumen and more solid stool.
Right versus left colon cancer
| Side | Typical presentation |
|---|---|
| Right (caecum/ascending) | Iron-deficiency anaemia, vague pain, mass; obstruction is late (wide lumen, liquid stool) |
| Left (descending/sigmoid) | Altered bowel habit, obstruction, PR bleeding, mass; annular 'apple-core' tumours |
Why this matters
- Recognising the side-specific pattern guides investigation; any change in bowel habit, PR bleeding or iron-deficiency anaemia in an older adult warrants colonic evaluation.
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