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True/False MCQ · Colorectal Cancer

Regarding risk factors for colorectal cancer, the following statements are TRUE:

Decide whether each statement is true or false.

  1. AA low-fibre, high-animal-fat diet increases risk
  2. BFamilial adenomatous polyposis (FAP) is a risk factor
  3. CA high-fibre diet is a major risk factor
  4. DInflammatory bowel disease is a risk factor
  5. EPrevious pelvic irradiation is a risk factor
Show answers and explanation
  • A. True
  • B. True
  • C. False: A high-fibre diet is protective against colorectal cancer, not a risk factor; it is a low-fibre diet that increases risk.
  • D. True
  • E. True

Risk factors for colorectal cancer

Diet, genetics and other factors contribute.

Risk factors
  • Diet: low fibre, high animal fat/red and processed meat, nitrosamines; smoking; alcohol.
  • Genetic: FAP, HNPCC.
  • Other: inflammatory bowel disease, previous pelvic irradiation.
The protective factor
  • A high-fibre diet is protective, not a risk factor.
Statement-by-statement verdict
Why A is true

A low-fibre, high-animal-fat diet increases risk.

Why B is true

FAP is a risk factor.

Why C is false

A high-fibre diet is protective, not a major risk factor.

Why D is true

IBD is a risk factor.

Why E is true

Previous pelvic irradiation is a risk factor.

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