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Flashcard · Gallstones and Biliary Disease

What are the types of gallstones, and what proportion are radio-opaque?

Answer
Cholesterol, pigment (from haemolysis), and mixed stones. Only about 10% are radio-opaque (those with sufficient calcium content), so most are not visible on plain X-ray - ultrasound is the imaging of choice.

Clinical relevance. Knowing most stones are radiolucent explains why ultrasound, not plain X-ray, is used to detect them.

More Detail

Types of gallstones

Gallstones are classified by composition, which relates to their cause and radiological appearance.

Types
  • Cholesterol stones: from cholesterol supersaturation (often associated with the classic risk factors).
  • Pigment stones: from excess bilirubin, e.g. in chronic haemolysis.
  • Mixed stones: the commonest, containing cholesterol and pigment.
Radiological appearance
  • Only about 10% are radio-opaque (those with enough calcium), so most are radiolucent and not seen on plain X-ray.
  • Ultrasound is the imaging of choice for detecting gallstones.

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