True/False MCQ · Red Cell Alloimmunisation in Pregnancy
Concerning the diagnosis and monitoring of fetal anaemia in alloimmunisation, which of the following statements are TRUE?
- AMCA peak systolic velocity correlates with fetal anaemia
- BA normal MCA peak systolic velocity indicates severe anaemia
- CAmniotic fluid optical density at 450 nm measures glucose
- DThe indirect Coombs test detects free maternal antibodies
- ECell-free fetal DNA can determine fetal RhD status
Show answers and explanation
- A. True
- B. False: A normal MCA peak systolic velocity is reassuring, not a sign of severe anaemia.
- C. False: Amniotic fluid OD 450 nm measures bilirubin, not glucose.
- D. True
- E. True
Diagnosis and monitoring
- MCA peak systolic velocity correlates with fetal anaemia.
- Indirect Coombs detects free maternal antibodies; cell-free fetal DNA determines fetal RhD status.
- Amniotic fluid OD 450 nm measures bilirubin.
Why A is true
MCA peak systolic velocity correlates with anaemia.
Why B is false
A normal MCA velocity is reassuring, not a sign of severe anaemia.
Why C is false
OD 450 nm measures bilirubin, not glucose.
Why D is true
The indirect Coombs test detects free maternal antibodies.
Why E is true
Cell-free fetal DNA determines fetal RhD status.
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