How common and important is colorectal cancer?

Colorectal cancer is the third most frequent cancer worldwide, with a rising incidence. The lifetime risk is about 1 in 23 for men and 1 in 26 for women. It is usually an adenocarcinoma and is often curable if detected early.

Clinical relevance. Knowing colorectal cancer is common and curable early underlines the value of screening and prompt investigation.

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Importance of colorectal cancer

Colorectal cancer is a major and increasingly common cancer that is often curable when caught early.

Frequency

• The third most frequent cancer worldwide; incidence is rising.
• Lifetime risk: about 1 in 23 for men and 1 in 26 for women.

Nature

• Usually an adenocarcinoma, arising mostly from pre-existing adenomas.
• Typically occurs in patients over 50, with a peak in later decades.

Why it matters

• Early detection (screening, prompt investigation of symptoms) markedly improves the chance of cure.